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If the patient was already being treated with a vasopressor at baseline, that agent was replaced as soon as possible with the trial-drug solution. If the patient was already receiving dopamine and this agent could not be discontinued after introduction of the trial-drug solution, the dopamine was replaced with an open-label norepinephrine infusion. Open-label dopamine was not allowed at any time. Epinephrine and vasopressin were used only as rescue therapy. Inotropic agents could be used, if needed, to increase cardiac output.


James Naismith, I learned, was a bit different. “I was only three when he passed away [in 1939],” said his grandson, James Naismith, 78, of Corpus Christi, Texas. “He was known as a tenderhearted man, but he also had”—the doctor’s namesake pauses—“the polite term is ‘firmness of mind.’ It’s kind of a family trait. He devoted his life to improving the lives of others through physical activity, through games. That took time.
The rate of death at 28 days in this study was close to 50%, which is to be expected in a study with very few exclusion criteria and is similar to the rate in previous observational studies.3,9,21-24 Our trial was a pragmatic study that included all patients who were treated for shock states, and therefore, it has high external validity. The study design allowed for maximal exposure to the study drug, since we included patients who had received open-label vasopressors for a maximum of 4 hours before randomization and since during the 28-day study period, the study drug was withdrawn last when patients were weaned from vasopressor therapies and was resumed first if resumption of vasopressor therapy was necessary.
Finally, to make things even more complicated, it is likely that the roles of the lower body muscles may differ according to if: (1) the jump is maximal or sub-maximal, (2) long-term training has occurred, and (3) the individual has a “hip-dominant” or a “knee-dominant” technique. Indeed, the vertical jump is more dependent upon the hip extensors in maximal jumps, compared to in sub-maximal ones. And after long-term jumping training, the increase in the amount of work done in the jump by the hip extensors is related to the increase in height, while the increase in the amount of work done by the knee extensors is not.
There are a number of variations on the windmill, the most common being the aforementioned one- or two-hand variants. In these cases, the windmill motion may be performed with the previously discussed one-arm technique and finished with one- or two-hands, or the player may control the ball with two hands, with both arms performing the windmill motion, finishing with one or both hands. Additionally, the ball may be cuffed between the hand and the forearm—generally with the dominant hand. The cuff technique provides better ball security, allowing for a faster windmill motion and increased force exerted on the basket at finish, with either one or both hands. Using the cuffing method, players are also afforded the opportunity of performing the windmill motion towards the front (counterclockwise), a technique exploited by French athlete Kadour Ziani when he pioneered his trademark double-windmill.
Vertical jump measurements are used primarily in athletic circles to measure performance. The most common sports in which one's vertical jump is measured are track and field, netball, basketball, football, and volleyball, but many sports measure their players' vertical jumping ability during physical examinations. In addition, single and multiple vertical jumps are occasionally used to assess muscular strength and anaerobic power in athletes.[3]
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