If the patient was already being treated with a vasopressor at baseline, that agent was replaced as soon as possible with the trial-drug solution. If the patient was already receiving dopamine and this agent could not be discontinued after introduction of the trial-drug solution, the dopamine was replaced with an open-label norepinephrine infusion. Open-label dopamine was not allowed at any time. Epinephrine and vasopressin were used only as rescue therapy. Inotropic agents could be used, if needed, to increase cardiac output.
I'm 33 yrs old, turning 34 in a month. I stand 5'7" and weigh 155 lbs. I used to touch the rim with both hands but now I can only touch the back board... I almost came close to dunking, but that was when I was 22 years old. I still dream of dunking one in...but I think the exercises that I used to do...don't seem to work anymore... Is it still possible for me to dunk even at this age?
Thus, dopamine and norepinephrine may have different effects on the kidney, the splanchnic region, and the pituitary axis, but the clinical implications of these differences are still uncertain. Consensus guidelines and expert recommendations suggest that either agent may be used as a first-choice vasopressor in patients with shock.6-8 However, observational studies have shown that the administration of dopamine may be associated with rates of death that are higher than those associated with the administration of norepinephrine.3,9,10 The Sepsis Occurrence in Acutely Ill Patients (SOAP) study,3 which involved 1058 patients who were in shock, showed that administration of dopamine was an independent risk factor for death in the intensive care unit (ICU). In a meta-analysis,11 only three randomized studies, with a total of just 62 patients, were identified that compared the effects of dopamine and norepinephrine in patients with septic shock. The lack of data from clinical trials in the face of growing observational evidence that norepinephrine may be associated with better outcomes called for a randomized, controlled trial. Our study was designed to evaluate whether the choice of norepinephrine over dopamine as the first-line vasopressor agent could reduce the rate of death among patients in shock.
slang To be bested by someone in a spectacular fashion and/or in a way that is humiliating to one. In basketball, to "dunk on" a defender is to perform a slam dunk over them, a move often considered humiliating to the defender. Here's the part of the debate where she really got dunked on&he totally destroys her argument! Sit down, son, you just got dunked on.
Athletes often do depth jumps with two plyo boxes: one to step off of and another to jump onto. Essentially, it’s a depth jump into a box jump. When doing this variation, make sure to leave enough room between the boxes to allow you to land and jump safely (3–5 feet between boxes should work). To advance within this progression, increase the height of the second box gradually as you develop more strength and power.
To begin, go up without a ball first. This will give you a great idea of where you’re at and just how close you are to being able to dunk. For beginners, you should focus on dunking with one hand. Your other hand should stay by your side to balance your body while you’re in the air. The two-handed dunk is awesome, but is surprisingly more of an advance dunk and should be an approach you build up to as you work on your dunking.
In the past, it has been possible for players to dunk a basketball and pull the rim down so hard that the glass backboard shatters, either around the rim itself or, at times, shattering the entire backboard, or the entire goal standard fails. Reinforced backboards and breakaway rims have minimized this at the college and professional levels, but it still happens at lower levels.
The following data were recorded every 6 hours for 48 hours, every 8 hours on days 3, 4, and 5, and once a day on days 6, 7, 14, 21, and 28: vital signs, hemodynamic variables (including systolic and diastolic arterial pressures, heart rate, central venous pressure, and, when possible, pulmonary-artery pressures), cardiac output, arterial and mixed-venous (or central venous) blood gas levels, doses of vasoactive agents, and respiratory conditions. Biologic variables, data on daily fluid balance, microbiologic data, and antibiotic therapy were recorded daily for the first 7 days and then on days 14, 21, and 28.
In the 1950s, Jim Pollard and Wilt Chamberlain had both dunked from the free throw line—15 feet from the basket. Chamberlain was able to dunk from the free-throw line without a running start, beginning his forward movement from within the top half of the free-throw circle. This was the catalyst for the 1956 NCAA rule change which requires that a shooter maintain both feet behind the line during a free-throw attempt.
The slam dunk is usually the highest percentage shot and a crowd-pleaser. Thus, the maneuver is often extracted from the basketball game and showcased in slam dunk contests such as the NBA Slam Dunk Contest held during the annual NBA All-Star Weekend. The first incarnation of the NBA Slam Dunk Contest was held during the half-time of the 1976 American Basketball Association All-Star Game.