In summary, although the rate of death did not differ significantly between the group of patients treated with dopamine and the group treated with norepinephrine, this study raises serious concerns about the safety of dopamine therapy, since dopamine, as compared with norepinephrine, was associated with more arrhythmias and with an increased rate of death in the subgroup of patients with cardiogenic shock.
IMPORTANT NOTE: Feb 2, 2019 - I am currently updating the site to have all the articles on the same format and also shooting new HD videos of the exercises in the library. For the duration of the this update I am selling Game Changers at an 80% discount (YES YOUR READ THAT RIGHT - 80% OFF the regular price). Instead of paying $47 you can pick up a copy of just $9. But hurry - this offer will be gone once I finish the updates.

The primary end point of the trial was the rate of death at 28 days. Secondary end points were the rates of death in the ICU, in the hospital, at 6 months, and at 12 months; the duration of stay in the ICU; the number of days without need for organ support (i.e., vasopressors, ventilators, or renal-replacement therapy); the time to attainment of hemodynamic stability (i.e., time to reach a mean arterial pressure of 65 mm Hg)16; the changes in hemodynamic variables; and the use of dobutamine or other inotropic agents. Adverse events were categorized as arrhythmias (i.e., ventricular tachycardia, ventricular fibrillation, or atrial fibrillation), myocardial necrosis, skin necrosis, ischemia in limbs or distal extremities, or secondary infections.17


I sent a video of my soccer ball dunk to Todd, the #fivefivedunker, who informed me that I was leading with the wrong leg. I’d been taking my last big step with my left foot, which, as a righty, was like swinging a bat cross-handed. A few days later I encountered a blogger and 43-year-old dunker named Andy Nicholson who showed me, among many other things, that I wasn’t the only one with blood on my hands. Nicholson was one of dozens of YouTubers, young and old (mostly young), who were documenting online their attempts to dunk. “Yes!” he yelled over the phone when I told him about the open sores on my fingers. “Those are badges of honor!”

Some days I would be doing leg exercises — you want to give yourself a 48-hour break between heavy lifting involving any given part of your body, to give yourself time to recover. Some days, I’d go out to the track and do a track workout like sprints. I was avoiding doing long-distance running, because I didn’t want to develop slow-twitch muscles. I wanted to concentrate on fast-twitch muscles. And then for fun, on the weekends, I would play soccer or pickup basketball. I was becoming a better athlete because of this. Not only was I faster and stronger, but I was also more confident, in terms of just the run of play in any of these team sports, because I was more athletic than I had been.
I met Janik at Velocity Sports Performance in Manhattan, where he trains clients. Janik was so handsome and well built he looked like an X-Men character. We talked about my athletic background and what I needed to do in order to dunk in ten weeks. He assigned me a three-days-a-week program that would improve my explosiveness and overall leg strength and told me to check back in three weeks to adjust it. "If you follow the program and your intensity level is high," he said, "I guarantee you’ll dunk again."
By emphasizing certain muscles in your legs, you can train your body for the force needed to leap high. Increasing your vertical jump will improve your rebounding, blocking, dunking, and make you an all-around better basketball player. Here are a few of CoachUp’s favorite exercises for improving your leg strength and vertical jump. If you ever need extra motivation to get through these exercises on a daily basis, just re-watch these gifs and focus up!
Like Todd and me, Nicholson was a two-foot jumper, and he echoed what Todd had told me was another flaw in my technique: “Your next-to-last step has to be a lot bigger. That big leap forward with your right foot—your penultimate step—that’s what allows you to explode off the ground.” To demonstrate, Nicholson sent me a video of Carter’s performance at the 2000 NBA Dunk Contest, which was a bit like showing a Monet to a finger painting kindergartner and saying, “No, like this.”
The primary end point of the trial was the rate of death at 28 days. Secondary end points were the rates of death in the ICU, in the hospital, at 6 months, and at 12 months; the duration of stay in the ICU; the number of days without need for organ support (i.e., vasopressors, ventilators, or renal-replacement therapy); the time to attainment of hemodynamic stability (i.e., time to reach a mean arterial pressure of 65 mm Hg)16; the changes in hemodynamic variables; and the use of dobutamine or other inotropic agents. Adverse events were categorized as arrhythmias (i.e., ventricular tachycardia, ventricular fibrillation, or atrial fibrillation), myocardial necrosis, skin necrosis, ischemia in limbs or distal extremities, or secondary infections.17
After four months of failing to pull off anything even resembling a real dunk, the planets aligned on Aug. 9: After at least 19 failed attempts that afternoon, I dunked a soccer ball on a middle school court whose rim measured 9' 11". (The original basketball, incidentally, was a soccer ball, property of Dr. Naismith’s employer, Springfield College.) Video from that afternoon shows me standing there, looking confused, in the moment afterward. Did that just happen? Failing had become so routine that even this small success felt foreign.
Each time you land, spring immediately back up. Don’t hesitate. The single beat that typically happens after we hit the ground is a natural reflex, and we may not even realize we’re doing it. But that extra pause has to go if we’re looking for a way to jump higher. Check the mirror or watch videos of yourself as you hit the ground. The momentary pause you may see between one vertical jump and the next may be holding you back. For more detail on how this works, visit the plyometrics section of our website.
An impressive vertical jump is the ultimate standard of lower-body power and explosiveness—an attribute that pays as many dividends in high-impact sports like basketball, football, and soccer as it gets you wide-eyed looks in the gym. Increase your hops, and chances are you’ll also be able to run faster, lift more weight, and maybe even throw down a dunk at your next pickup basketball game.
Data on hemodynamic variables and doses of vasoactive agents are shown in Figure 3 and Figure 4 in the Supplementary Appendix. The mean arterial pressure was similar in the two treatment groups at baseline, and it changed similarly over time, although it was slightly higher from 12 to 24 hours in the norepinephrine group. The doses of the study drug were similar in the two groups at all times. More patients in the dopamine group than in the norepinephrine group required open-label norepinephrine therapy at some point (26% vs. 20%, P<0.001), but the doses of open-label norepinephrine that were administered were similar in the two groups. The use of open-label epinephrine at any time was similar in the two groups (administered in 3.5% of patients in the dopamine group and in 2.3% of those in the norepinephrine group, P=0.10), as was the use of vasopressin (0.2% in both groups, P=0.67). Dobutamine was used more frequently in patients treated with norepinephrine, but 12 hours after randomization, the doses of dobutamine were significantly higher in patients treated with dopamine. The mean (±SD) time to the achievement of a mean arterial pressure of 65 mm Hg was similar in the two groups (6.3±5.6 hours in the dopamine group and 6.0±4.9 hours in the norepinephrine group, P=0.35). There were no major between-group differences in the total amounts of fluid given, although patients in the dopamine group received more fluids on day 1 than did patients in the norepinephrine group. Urine output was significantly higher during the first 24 hours after randomization among patients in the dopamine group than among those in the norepinephrine group, but this difference eventually disappeared, so that the fluid balance was quite similar between the two groups.
I am in grade 10, 15 years old and 6'1 3/4". I have big hands and can palm the ball...I could touch rim in grade 8 and getting closer to dunking everyday now..it literally takes no effort to touch rim now but whenever I go for the dunk I get the ball above rim easily but have trouble getting that wrist motion to actually throw the ball in the hoop...and help?

“There’s something about dunking a basketball that lures us in,” he said, reflecting on his first jam, during lunch period his sophomore year at De La Salle High in Concord, Calif., back when his driver’s license read 5' 11", 112 pounds. “It stokes the imagination. It’s something you always dream of doing. I have a friend whose father, at age 50, is trying to dunk.”
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Circulatory shock is a life-threatening condition that is associated with high mortality.1,2 The administration of fluids, which is the first-line therapeutic strategy, is often insufficient to stabilize the patient's condition, and adrenergic agents are frequently required to correct hypotension. Among these agents, dopamine and norepinephrine are used most frequently.3 Both of these agents influence alpha-adrenergic and beta-adrenergic receptors, but to different degrees. Alpha-adrenergic effects increase vascular tone but may decrease cardiac output and regional blood flow, especially in cutaneous, splanchnic, and renal beds. Beta-adrenergic effects help to maintain blood flow through inotropic and chronotropic effects and to increase splanchnic perfusion. This beta-adrenergic stimulation can have unwanted consequences as well, including increased cellular metabolism and immunosuppressive effects. Dopamine also stimulates dopaminergic receptors, resulting in a proportionately greater increase in splanchnic and renal perfusion, and it may facilitate resolution of lung edema.4 However, dopaminergic stimulation can have harmful immunologic effects by altering hypothalamo–pituitary function, resulting in a marked decrease in prolactin and growth hormone levels. 5

A strut is a major structural part of a suspension. It takes the place of the upper control arm and upper ball joint used in conventional suspensions. Because of its design, a strut is lighter and takes up less space than the shock absorbers in conventional suspension systems. Struts perform two main jobs. First, struts perform a damping function like shock absorbers. Internally, a strut is similar to a shock absorber. A piston is attached to the end of the piston rod and works against hydraulic fluid to control spring and suspension movement. Just like shock absorbers, the valving generates resistance to forces created by the up and down motion of the suspension. Also like shock absorbers, a strut is velocity sensitive, meaning that it is valved so that the amount of resistance can increase or decrease depending on how fast the suspension moves.

I just got the bike on Friday and used it twice over the weekend so this isn't a long-term review but my initial impression is highly favorable. I am a "serious" cyclist, which is not to say I'm a professional or anything like that but I log a lot of miles on my road bike and use high-end equipment. I've always hated hooking a bike up to an indoor trainer and I've avoided that type of training for many years. I finally went in on a spinning bike and I am very impressed with the results.


Important Update! – I have been receiving a few emails/comments on players tracking their jump during the course of their program. Please understand that what you are doing when completing a jump program is breaking down the muscle.  You aren’t going to see improvements mid-week because the muscle hasn’t healed properly. That’s why I suggest only checking how much you’ve improved at the end of each rest week. Rest is just as important as the routine. 
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