Circulatory shock is a life-threatening condition that is associated with high mortality.1,2 The administration of fluids, which is the first-line therapeutic strategy, is often insufficient to stabilize the patient's condition, and adrenergic agents are frequently required to correct hypotension. Among these agents, dopamine and norepinephrine are used most frequently.3 Both of these agents influence alpha-adrenergic and beta-adrenergic receptors, but to different degrees. Alpha-adrenergic effects increase vascular tone but may decrease cardiac output and regional blood flow, especially in cutaneous, splanchnic, and renal beds. Beta-adrenergic effects help to maintain blood flow through inotropic and chronotropic effects and to increase splanchnic perfusion. This beta-adrenergic stimulation can have unwanted consequences as well, including increased cellular metabolism and immunosuppressive effects. Dopamine also stimulates dopaminergic receptors, resulting in a proportionately greater increase in splanchnic and renal perfusion, and it may facilitate resolution of lung edema.4 However, dopaminergic stimulation can have harmful immunologic effects by altering hypothalamo–pituitary function, resulting in a marked decrease in prolactin and growth hormone levels. 5
To perform two-foot dunks, jumpers bend their knees very deeply and spend a lot more time on the ground loading the jump. This increased time during takeoff is useful because it allows the athlete to transfer force into the ground thereby improving height. Using this approach makes it more difficult to transform speed into jump height making a fast approach far less useful than in one-foot jumping.
So, you are probably wondering what the difference is right? Well, the first big difference is in the look. If you want to look the best while doing your jump shoes the Jump 99 will be one complete unit that will look better than the Jumpsoles. Now that doesn't have anything to do with jumping higher but we know players care about how they look when training so that is an advantage for the Jump 99 shoe.