Randomization was performed in computer-generated, permuted blocks of 6 to 10, stratified according to the participating ICU. Treatment assignments and a five-digit reference number were placed in sealed, opaque envelopes, which were opened by the person responsible for the preparation of the trial-drug solutions. The solutions of norepinephrine or dopamine were prepared in vials or syringes according to the preference of the local ICU. Each vial or syringe was then labeled with its randomly allocated number. The doctors and nurses administering the drugs, as well as the local investigators and research personnel who collected data, were unaware of the treatment assignments. The trial was approved by the ethics committee at each participating center. Written informed consent was obtained from all patients or next of kin.
As an athlete pushes off the ground, he or she must overcome his/her own body weight. The lighter the athlete, the less force is necessary to do this. Imagine trying to jump as high as you can and then immediately repeating this same test wearing a 20-pound vest. It's obvious that the second jump will be much smaller. Now, imagine how much higher you could jump if you were 20 pounds lighter.
Sets/Reps: For general strength and lower-body development, Benguche recommends 3–6 sets of 3–8 reps with moderate loading—70%–85% of your one-rep max (1RM). For developing more speed and power, he recommends lighter loads (55%–70% of 1RM) for 3–6 sets of 2–5 reps. Squats performed with light weights but done so explosively that your feet leave the floor when you come up are called jump squats (see “Progressions” below).
An important component of maximizing height in a vertical jump is attributed to the use of counter-movements of the legs and arm swings prior to take off, as both of these actions have been shown to significantly increase the body’s center of mass rise. The counter-movement of the legs, a quick bend of the knees which lowers the center of mass prior to springing upwards, has been shown to improve jump height by 12% compared to jumping without the counter-movement. This is attributed to the stretch shortening cycle of the leg muscles enabling the muscles to create more contractile energy. Furthermore, jump height can be increased another 10% by executing arm swings during the take off phase of the jump compared to if no arm swings are utilized. This involves lowering the arms distally and posteriorly during the leg counter-movements, and powerfully thrusting the arms up and over the head as the leg extension phase begins. As the arms complete the swinging movement they pull up on the lower body causing the lower musculature to contract more rapidly, hence aiding in greater jump height. Despite these increases due to technical adjustments, it appears as if optimizing both the force producing and elastic properties of the musculotendinous system in the lower limbs is largely determined by genetics and partially mutable through resistance exercise training.